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Related Experiment Videos

A dynamic bubble trap reduces microbubbles during cardiopulmonary bypass: a case study.

M Schönburg1, P Urbanek, G Erhardt

  • 1Kerckhoff-Klinik GmbH Benekestr, 2-8 61231 Bad Nauhelm Germany.

The Journal of Extra-Corporeal Technology
|January 9, 2001
PubMed
Summary
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A dynamic bubble trap effectively removes harmful air microbubbles during cardiopulmonary bypass, significantly reducing the risk of postoperative neurologic dysfunction in patients.

Area of Science:

  • Cardiovascular Surgery
  • Neurology
  • Biomedical Engineering

Background:

  • Cardiopulmonary bypass (CPB) can lead to cerebral microemboli, a major cause of postoperative neurologic dysfunction.
  • Air microbubbles are identified as the primary culprits responsible for these embolic events.
  • Existing filtration methods may not adequately remove all harmful microbubbles.

Observation:

  • A novel dynamic bubble trap (DBT) was developed to address microbubble elimination in extracorporeal circulation.
  • High concentrations of microbubbles, some exceeding 40 microns, were observed in the arterial line despite standard filtration.
  • The DBT was implemented during coronary artery bypass grafting (CABG) procedures.

Findings:

  • The dynamic bubble trap significantly reduced the number of large microbubbles in the arterial line.

Related Experiment Videos

  • In patient 1, microbubble counts decreased from 2,267 to 67.
  • In patient 2, microbubble counts decreased from 897 to 61.

    • Implications:

    • The DBT demonstrates a high efficacy in mitigating microbubble load during CPB.
    • This technology holds potential for improving neurological outcomes after cardiac surgery.
    • Further research and clinical integration of the DBT could enhance patient safety in CPB procedures.