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[High-dose thiotepa chemotherapy in children]
D G Izhogin1, V K Boiarshinov, I S Dolgonolov
1N.N. Blokhin Center for Oncology Research, Russian Academy of Medical Sciences, Moscow.
Voprosy Onkologii
|January 9, 2001
Abstract:
High-dose thiotepa (800-900 mg/m2) polychemotherapy following combined treatment resulted in high toxicity and lethality. 600 mg/m2 proved optimal for double-conditioning regimens since it exerted antitumor effect without causing fatal complications.