[Relationship between chronic viral hepatitis and hepatocellular carcinoma]

V E Karev¹, V A Tsinzerling, D V Komarova

¹State University, S.P. Botkin Municipal Infectious Hospital No. 30, St. Petersburg.

|January 9, 2001

Abstract:

Recent years have seen a correlation between the rise in morbidity and lethality from chronic viral hepatitis and that of hepatocellular carcinoma. Present-day methods of hepatotropic viruses (HBV and HCV) identification point to a growing role of chronic viral hepatitis in etiology of cirrhosis which gives rise to hepatocellular cancers. A study of 49 cases based on sectional material established hepatocellular carcinoma development in smoldering chronic viral hepatitis caused by B or C virus or their combination. An immunohistochemical investigation (29) identified differences in hepatitis B and C virus antigen expression in tumor and adjacent hepatic tissue.

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Abstract:

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