Related Experiment Video
Updated: Aug 2, 2026
08:16
Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro
Published on: March 21, 2015
[Low-intensity laser therapy in pediatric oncology]
S A Balakirev1, L I Gusev, M B Kazanova
1Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Center for Oncology Research, Russian Academy of Medical Sciences, Moscow.
Voprosy Onkologii
|January 9, 2001
Summary
Low-intensity laser radiotherapy (LILR) significantly reduced recovery times for pediatric patients undergoing radiation injury and chemotherapy. This therapy boosts mononuclear cells, increasing immune response factors like IL-1 and FNO.
Area of Science:
- Oncology
- Immunology
- Radiotherapy
Context:
- Pediatric patients undergoing cancer treatment often experience radiation injury and chemotherapy complications.
- Current management strategies can be time-consuming and may have limited efficacy.
Purpose:
- To evaluate the efficacy of low-intensity laser radiotherapy (LILR) in managing radiation injury and chemotherapy complications in pediatric patients.
- To investigate the immunological mechanisms underlying LILR's therapeutic effects.
Summary:
- Application of low-intensity laser radiotherapy (LILR) reduced the management time for radiation injury and chemotherapy complications in pediatric patients by 1.5-2 fold.
- LILR exposure increased mononuclear (MN) cell levels in donor blood.
- This increase in MN cells correlated with higher concentrations of key immune response factors, including Interleukin-1 (IL-1) and Factor Necrosis Omega (FNO).
Impact:
- LILR offers a promising therapeutic approach to accelerate recovery in pediatric oncology patients.
- The findings elucidate LILR's immunomodulatory effects, potentially paving the way for novel treatment strategies.
- This research contributes to optimizing supportive care during pediatric cancer treatment.
