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3.6% of sera from random blood donors were found to contain antibody to vaccinia antigen(s) when screened by IEOP. Antibodies of the strength previously suggested as suitable for use in the preparation of anti-vaccinia immune globulin (titre 2 or more) were only found in revaccinated donors, especially but not exclusively those bled within about 3 months of last vaccination.
3.6% of sera from random blood donors were found to contain antibody to vaccinia antigen(s) when screened by IEOP. Antibodies of the strength previously suggested as suitable for use in the preparation of anti-vaccinia immune globulin (titre 2 or more) were only found in revaccinated donors, especially but not exclusively those bled within about 3 months of last vaccination.