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Brain biopsy sampling by using prospective stereotaxis and a trajectory guide
1Department of Neurosurgery, University of Minnesota School of Medicine, Minneapolis, USA. hallx003@tc.umn.edu
Journal of Neurosurgery
|January 9, 2001
Summary
A new skull-mounted trajectory guide combined with prospective stereotaxis offers a safe and accurate method for intraoperative magnetic resonance (MR) imaging-guided brain biopsies, yielding diagnostic tissue efficiently.
Area of Science:
- Neurosurgery
- Medical Imaging
- Biopsy Techniques
Background:
- Intraoperative magnetic resonance (MR) imaging-guided brain biopsy is crucial for accurate diagnosis.
- Traditional methods may face challenges in precise trajectory alignment.
Purpose of the Study:
- To evaluate the initial results of a novel skull-mounted trajectory guide for MR imaging-guided brain biopsy.
- To assess the efficacy of prospective stereotaxis for surgical trajectory alignment in these procedures.
Main Methods:
- Utilized a skull-mounted trajectory guide with prospective stereotaxis in 38 patients (40 procedures) using a 1.5-tesla MR imager.
- Employed T2-weighted half-Fourier acquisition single-shot turbo spin-echo (HASTE) images for trajectory determination and alignment.
- Confirmed specimen adequacy and assessed for hemorrhage using intraoperative and postoperative MR imaging.
Main Results:
- Trajectory determination and alignment were efficient, taking less than 5 minutes.
- All biopsy procedures successfully yielded diagnostic tissue.
- No clinically significant hemorrhage was observed; one patient experienced transient hemiparesis.
Conclusions:
- The trajectory guide, in conjunction with prospective stereotaxis, proved to be a safe and accurate tool for brain biopsy.
- This approach facilitates efficient and reliable tissue sampling under MR guidance.
