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Updated: Aug 7, 2026

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Published on: January 5, 2017
Poromas of the head and neck
T O Moore1, H L Orman, S K Orman
1Department of Medicine, Division of Dermatology, Pennsylvania State University, Hershey, USA.
Background:
The "eccrine" poroma is a benign neoplasm previously thought to originate from the eccrine sweat gland. Early studies suggested that these were primarily lesions of the hairless acral surfaces.
Objective:
This article reports the clinical and histologic findings of 10 cases of poroma of the head and neck area.
Methods:
The clinical and histologic findings of 10 cases of poroma of the head and neck area are compared with 10 poromas occurring on the extremities.
Results:
Some poromas demonstrated evidence for apocrine origin. Unlike poromas found on the extremities, head and neck poromas were usually asymptomatic and were never correctly diagnosed clinically. Although 9 of 10 poromas on the extremities occurred in male patients, the head and neck poromas showed no gender predilection.
Conclusion:
Clinicians should be aware that poromas can occur in the head and neck area and may be of apocrine origin.
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