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Rhinosinusitis in severe asthma.

M Bresciani1, L Paradis, A Des Roches

  • 1Service des Maladies Respiratoires and INSERM U 454, Hôpital Arnaud de Villeneuve, CHU de Montpellier, Montpellier, France.

The Journal of Allergy and Clinical Immunology
|January 10, 2001
PubMed
Summary
This summary is machine-generated.

Chronic rhinosinusitis is common in asthma patients. Severe steroid-dependent asthma shows greater sinonasal involvement on clinical and CT scans, despite similar rhinosinusitis symptom frequency.

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Area of Science:

  • Pulmonology
  • Otolaryngology
  • Medical Imaging

Background:

  • Chronic rhinosinusitis frequently co-occurs with asthma.
  • Sinonasal involvement in severe steroid-dependent asthma remains poorly understood.

Purpose of the Study:

  • To assess chronic rhinosinusitis in severe steroid-dependent asthma patients.
  • Utilized clinical scoring and computed tomography (CT) scanning for evaluation.

Main Methods:

  • Compared 35 severe steroid-dependent asthma patients with 34 mild-to-moderate asthma patients.
  • Assessed sinonasal involvement using clinical and CT scan severity scores.
  • Evaluated airflow obstruction, therapy needs, and asthma triggers.

Main Results:

  • Similar rhinosinusitis symptom prevalence (74% vs. 70%) in severe vs. mild-to-moderate asthma.
  • Higher abnormal CT scan rates in severe asthma (100% vs. 88%).
  • Significantly higher clinical and CT scan severity scores in severe steroid-dependent asthma patients.

Conclusions:

  • Rhinosinusitis frequency is similar across asthma severities.
  • Severe steroid-dependent asthma exhibits significantly greater sinonasal involvement via clinical and CT assessment.