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Endogenous opiates: 1999.

A L Vaccarino1, A J Kastin

  • 1Department of Psychology, University of New Orleans, New Orleans, LA 70148, USA. avaccari@uno.edu

Peptides
|January 11, 2001
PubMed
Summary
This summary is machine-generated.

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This review covers 1999 research on the behavioral effects of opiate peptides and antagonists, excluding analgesia but including stress-induced pain relief. It details impacts on various functions, from mood and reward to physiological responses.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Behavioral Science

Background:

  • The opiate system plays a crucial role in regulating numerous physiological and behavioral processes.
  • Annual reviews are essential for synthesizing the rapidly evolving research in this field.

Purpose of the Study:

  • To summarize research published in 1999 concerning the behavioral effects of opiate peptides and antagonists.
  • To provide an overview of the opiate system's influence on a wide range of functions, excluding purely analgesic effects.

Main Methods:

  • Literature review of scientific papers published in 1999.
  • Focus on studies investigating behavioral outcomes associated with opiate system modulation.
  • Inclusion of stress-induced analgesia research.

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Main Results:

  • Opiate peptides and antagonists influence diverse behaviors including stress responses, learning, reward, and substance abuse.
  • The review covers effects on eating, drinking, sexual activity, mood, neurological disorders, and general activity.
  • Impacts on cardiovascular, respiratory, thermoregulatory, gastrointestinal, renal, hepatic, and immunologic functions are also detailed.

Conclusions:

  • Research in 1999 significantly advanced the understanding of the opiate system's broad behavioral and physiological influence.
  • The opiate system is implicated in a wide array of complex behaviors and bodily functions, highlighting its systemic importance.