Nursing management considerations with trastuzumab (herceptin)
1Comprehensive Cancer Research Group/Intercenter Cancer Research Group, Mount Sinai Comprehensive Cancer Center, Miami Beach, FL, USA.
Objectives:
To review nursing management consideration for patients with advanced breast cancer who are candidates for trastuzumab.
Data Sources:
Research articles and the trastuzumab product insert.
Conclusions:
Identification of appropriate candidates for trastuzumab therapy should include a review of HER2 status, previous treatments, presence of comorbid diseases, and determination of cardiac function.
Implications For Nursing Practice:
Nurses will manage the administration of trastuzumab. Therefore, they must understand how antibodies work at the cellular level, how to treat infusion-related events, and how to choose the best candidates for biological therapy.
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