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Synthesis and antimycobacterial activity of some 4H-1,2,4-triazin-5-one derivatives
M G Mamolo1, V Falagiani, D Zampieri
1Dipartimento di Scienze Farmaceutiche, Università di Trieste, Italy. mamolo@univ.trieste.it
Abstract:
6-[(Arylmethylenamino)carbonyl]-3-(pyridin-2-yl)-4H-1,2,4-triazin-5-one derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed interesting activity against a strain of Mycobacterium tuberculosis.