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The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
Published on: October 7, 2016
Synthesis of radiolabeled congeners of the carbomers: (14)C-labeled poly(acrylic acid)s
R G Riley1, J D Smart, J Tsibouklis
1School of Pharmacy and Biomedical Sciences, University of Portsmouth, St. Michael's Building, White Swan Road, Portsmouth PO1 2DT, UK.
Abstract:
A general method for the synthesis of (14)C-acrylic acid is described in detail. The material is used for the synthesis of a range of radiolabeled poly(acrylic acid)s in which the (14)C-label forms an integral part of the polymer backbone. The chemical structure of the synthesized polymers is examined in the light of spectroscopic data, molecular weight determinations, and rheological studies.
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