Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Multiple sclerosis and new imaging methods].

J Mihale1, J Bilicky, R Kadlecik

  • 11st Dpt of Neurology FN, Mickiewiczova 13, SK-813 69 Bratislava 1, Slovakia. bll@fmed.uniba.sk

Bratislavske Lekarske Listy
|January 12, 2001
PubMed
Summary

Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) aid in diagnosing multiple sclerosis (MS) by visualizing central nervous system involvement. While MRI is valuable for supporting MS diagnosis, current imaging techniques do not fully confirm it.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coronavirus pandemic and the Slovak medical faculties.

Bratislavske lekarske listy·2020
Same author

The importance of interictal electroencephalography in paroxysmal states.

Bratislavske lekarske listy·2014
Same author

A radiologic correlation with the basic functional neuroanatomy of the brain.

Bratislavske lekarske listy·2014
Same author

[Peripheral arterial disease of extremities--guidelines for diagnostic and treatment].

Vnitrni lekarstvi·2013
Same author

Mild traumatic brain injury.

European journal of neurology·2012
Same author

Clinical, neurophysiologic, neuropsychological findings and short genetic analysis in patients with idiopathic Parkinson's disease.

Bratislavske lekarske listy·2010

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Central nervous system (CNS) involvement in multiple sclerosis (MS) is increasingly visualized using MRI and CT.
  • Advanced imaging techniques like "magnetisation transfer imaging" and high-resolution methods are under investigation.
  • Routine brain and spinal cord examinations often utilize "dual echo spin images" and Flair sequences.

Purpose of the Study:

  • To support the clinical diagnosis of multiple sclerosis (MS).
  • To evaluate the efficacy of MRI and CT in diagnosing MS.

Main Methods:

  • 131 patients with suspected multiple sclerosis (MS) underwent both CT and MRI.
  • Examinations included brain and spinal cord imaging using specific MRI sequences (T1 VO, T2 VO).
  • Findings were evaluated based on established criteria (Fazekasz, American Multiple Sclerosis Association).

Related Experiment Videos

Main Results:

  • MRI confirmed MS diagnosis in 98 out of 131 patients.
  • CT identified pathological findings in only 24% of patients initially diagnosed with MS.
  • MRI detected characteristic hyperintensive lesions in the white matter, cerebellum, and spinal cord, supporting diagnosis in all cases where it was firmly established.
  • MRI did not sufficiently verify the diagnosis in 33 patients with tentative diagnoses and less pronounced neurological findings.

Conclusions:

  • Current CNS imaging techniques, including CT and MRI, primarily support rather than definitively confirm multiple sclerosis (MS) diagnosis.
  • MRI is a crucial tool for assessing MS, particularly in detecting characteristic lesions.
  • Further advancements in imaging may enhance diagnostic certainty for MS.