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[Left ventricular hypertrophy in hypertension].

M A Ghanem Wisam1, J Murin, J Bulas

  • 11st Dpt of Internal Medicine FN, Mickiewiczova 13, SK-813 69 Bratislava 1, Slovakia. wisam.ghanem@usa.net

Bratislavske Lekarske Listy
|January 12, 2001
PubMed
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Left ventricular hypertrophy (LVH) in hypertensive patients is linked to more cardiovascular complications like heart failure and kidney issues. Early detection of LVH in hypertension is recommended to manage the disease course.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Diagnostic Imaging

Background:

  • Left ventricular hypertrophy (LVH) is a known complication of hypertension.
  • Other atherosclerosis risk factors like hyperlipidemia and smoking can worsen hypertension prognosis.
  • The study investigates clinical differences in hypertensive patients with and without LVH.

Purpose of the Study:

  • To compare clinical findings in hypertensive patients with and without echocardiographically defined LVH.
  • To assess the impact of LVH on cardiovascular complications in hypertension.
  • To evaluate the prognostic significance of LVH in hypertensive individuals.

Main Methods:

  • Retrospective analysis of 185 hypertensive patients' hospital records (1996-1999).
  • LVH defined by echocardiography (Penn convention): LV mass index > 134 g/m2 (men), > 110 g/m2 (women).

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  • Patients matched for demographics, hyperlipidemia, and smoking; diabetes and obesity excluded.

    • Main Results:

    • LVH present in 109 patients (mean age 66.7 years), absent in 76 (mean age 64.7 years).
    • Statistically significant higher incidence of heart failure, myocardial infarction, renal failure, and mitral regurgitation in LVH-positive patients.
    • Stroke incidence was slightly higher in LVH-negative patients.

    Conclusions:

    • Hypertensive patients with LVH experience a more complicated disease course.
    • LVH is a significant complicating factor in arterial hypertension.
    • Routine examination for LVH in hypertensive patients is recommended for better disease management.