Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Subacute endocarditis caused by Actinobacillus actinomycetemcomitans].

S L Belloch1, M Salavert, J Lacruz

  • 1Unidad de Enfermedades Infecciosas, Hospital Universitario La Fe, Valencia.

Enfermedades Infecciosas Y Microbiologia Clinica
|January 12, 2001
PubMed
Summary

Actinobacillus actinomycetemcomitans endocarditis (EAA) is rare, often originating from the mouth, and typically presents subacutely. Prompt antibiotic treatment, often with penicillin and aminoglycosides, leads to excellent outcomes without the need for surgery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Candent issues in pneumonia. Reflections from the Fifth Annual Meeting of Spanish Experts 2023.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2024
Same author

Reduction in the risk of progression of solid organ transplant recipients infected by SARS-CoV-2 treated with monoclonal antibodies.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2023
Same author

Norovirus infection as a model of chronic or recurrent infection in common variable immunodeficiency.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2022
Same author

Current management of CMV infection in cancer patients (solid tumors). Epidemiology and therapeutic strategies.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2022
Same author

Treatment of Clostridioides difficile infection: from guidelines to clinical practice.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2022
Same author

A systematic literature review and expert consensus on risk factors associated to infection progression in adult patients with respiratory tract or rectal colonisation by carbapenem-resistant Gram-negative bacteria.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2022

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Endocarditis caused by Actinobacillus actinomycetemcomitans (EAA) is a rare clinical entity.
  • This study describes hospital-observed cases of EAA, focusing on patient demographics, clinical presentation, and treatment outcomes.

Observation:

  • Four cases of EAA were identified over a twelve-year period.
  • Patients often had pre-existing valvular prostheses or a history of dental manipulation.
  • Clinical presentation was typically subacute, with some cases exhibiting delayed manifestations like neurological deficits or Osler's nodes.

Findings:

  • Actinobacillus actinomycetemcomitans cultures required prolonged incubation and specific media conditions for growth.
  • All isolates demonstrated susceptibility to penicillins, aminopenicillins, aminoglycosides, and quinolones.

Related Experiment Videos

  • Antibiotic therapy, primarily penicillin G alone or combined with aminoglycosides, successfully managed the infection in most patients.

    • Implications:

    • EAA can occur without prior cardiac disease, with oral foci being a common entry point.
    • The subacute and sometimes atypical presentation can delay diagnosis.
    • Effective treatment involves antibiotic combinations, and excellent prognoses are achievable without surgical intervention.