Related Experiment Videos
The mannan-binding-lectin pathway of the innate immune response
M Gadjeva1, S Thiel, J C Jensenius
1The Center for Blood Research, Harvard Medical School, 221 Longwood Avenue, Boston, MA 01215, USA. gadjeva@cbr.med.harvard.edu
Current Opinion in Immunology
|January 13, 2001
Abstract:
Dramatic progress has been achieved during the past year in our understanding of how the complement system is activated via the mannan-binding-lectin pathway. Surprising discoveries have changed our concepts of the complexes that are formed upon engagement of mannan-binding lectin with its serine proteases.