[Antibiotic prophylaxis in the surgical treatment of inguinal hernia: need or habit?]
1I Scuola di Specializzazione in Chirurgia Generale Azienda Ospedaliera, Università degli Studi di Roma La Sapienza, Roma. marcobarreca@libero.it
Background:
Prophylactic antibiotics are recommended for clean-contaminated and selected contaminated surgery. In clean surgery antibiotics are suggested if the operation involves the insertion of prosthetic devices and a potential infection is expected to cause serious morbidity or mortality. Inguinal hernia repair is a clean operation, infections are rare; they can usually be cured without removing the prosthesis and recurrence is uncommon even after removal of the mesh. Aim of the study is to evaluate whether the lack of antimicrobial prophylaxis increases the risk of postoperative infections in patients treated for groin hernia, compared to those treated with prophylaxis.
Methods:
One hundred and forty-eight patients underwent inguinal hernia repair with mesh: 64 patients (43%) received 2 g cefotaxime by intravenous bolus about 30 minutes before the operation, 84 patients (57%) did not receive any antimicrobic prophylaxis. Mean follow-up was 13 months (range 1-31 months) for both groups.
Results:
We did not observe any major complication. Among both groups, no patient had developed infection at one week and one month after surgery.
Conclusions:
In personal experience, any advantage in terms of prevention of infections with antibiotic prophylaxis in patients operated on for groin hernia has been observed. A review of the literature showed no general agreement on this subject with different risk of infections in different trials. A new prospective randomized trial is necessary to clarify this topic.
Insights
This study found no increased risk of postoperative infection in patients undergoing inguinal hernia repair without prophylactic antibiotics. Antimicrobial prophylaxis did not demonstrate a benefit in preventing surgical site infections in this clean surgery cohort.
Area of Science:
- Surgical infection prevention
- Hernia surgery outcomes
- Antimicrobial stewardship
Background:
- Prophylactic antibiotics are standard for clean-contaminated surgery and recommended for clean surgery with prosthetic devices.
- Inguinal hernia repair is a clean procedure where infections are infrequent and typically manageable without mesh removal.
- The study aimed to assess if omitting antimicrobial prophylaxis impacts postoperative infection rates in groin hernia repair.
Purpose of the Study:
- To evaluate the necessity of antimicrobial prophylaxis in preventing surgical site infections after inguinal hernia repair.
- To compare infection rates between patients who received prophylactic antibiotics and those who did not.
Main Methods:
- A cohort of 148 patients undergoing mesh inguinal hernia repair was analyzed.
- 64 patients received cefotaxime prophylaxis, while 84 did not receive any antimicrobial prophylaxis.
- Follow-up averaged 13 months to monitor for postoperative complications.
Main Results:
- No major complications were reported in either group.
- Surgical site infections were absent at one week and one month post-surgery in all patients.
Conclusions:
- The study observed no advantage of antibiotic prophylaxis in preventing infections for groin hernia repair patients.
- Literature review indicates no consensus on antibiotic prophylaxis for this procedure, with varying infection risks reported.
- Further prospective randomized trials are needed to definitively clarify the role of antibiotic prophylaxis in inguinal hernia repair.
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