Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

AIDS and Chagas' disease.

M Corti1

  • 1Unit 10, Muñiz Infectious Diseases Hospital, Buenos Aires, Argentina. marcelocorti@ciudad.com.ar

AIDS Patient Care and Stds
|January 13, 2001
PubMed
Summary

Chagas disease reactivation in AIDS patients can mimic brain tumors or infections. Early diagnosis and treatment are crucial due to the poor prognosis of untreated cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancements in AAV-mediated Gene Therapy for Pompe Disease.

Journal of neuromuscular diseases·2019
Same author

Development of an integrated chromatographic system for ω-transaminase-IMER characterization useful for flow-chemistry applications.

Journal of pharmaceutical and biomedical analysis·2019
Same author

Survival and recurrent venous thromboembolism in patients with first proximal or isolated distal deep vein thrombosis and no pulmonary embolism.

Journal of thrombosis and haemostasis : JTH·2017
Same author

Water response to ganglioside GM1 surface remodelling.

Biochimica et biophysica acta. General subjects·2016
Same author

Characterization of magnetic nanoparticles from Magnetospirillum Gryphiswaldense as potential theranostics tools.

Contrast media & molecular imaging·2015
Same author

A majority rule approach for region-of-interest-guided streamline fiber tractography.

Brain imaging and behavior·2015

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Chagas disease reactivation is a concern in immunocompromised individuals, particularly those with Acquired Immunodeficiency Syndrome (AIDS).
  • Reactivated Chagas disease in AIDS patients can manifest neurologically, mimicking other serious conditions.
  • Distinguishing Chagasic brain lesions from other opportunistic infections or tumors is clinically challenging.

Purpose of the Study:

  • To highlight the neurological manifestations of Chagas disease reactivation in patients with AIDS.
  • To emphasize the diagnostic challenges posed by these presentations.
  • To underscore the urgent need for effective treatments.

Main Methods:

  • This abstract is based on a review of clinical presentations and outcomes.
  • Literature review focusing on Chagas disease reactivation in the context of AIDS.
  • Analysis of differential diagnoses for central nervous system (CNS) lesions in AIDS patients.

Main Results:

  • Chagas disease reactivation in AIDS patients frequently presents as a CNS tumor-like lesion.
  • These presentations are often indistinguishable from toxoplasma encephalitis or primary CNS lymphoma.
  • Acute diffuse meningoencephalitis is another possible, though less common, manifestation.

Conclusions:

  • Chagas disease reactivation in AIDS patients requires high clinical suspicion for accurate diagnosis.
  • Prompt and effective therapeutic interventions are essential given the grave prognosis of untreated cases.
  • Further research into safe and effective treatments for neuro-Chagas disease in AIDS is warranted.

Related Experiment Videos