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Updated: Oct 9, 2026

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
Published on: November 1, 2012
A highly non-ideal solution: the contractile system of skeletal muscle
1Dipartimento di Biochimica e Biologia Molecolare, Università di Ferrara, Italy. gre@ifeuniv.unife.it
Abstract:
The contractile system is a highly non-ideal solution. The activities of its components must be determined in order to achieve a meaningful representation of cross-bridge kinetics and of chemio-mechanical transduction. Osmotic techniques may help in this respect. A few examples are presented. Protein osmotic pressure influences cross-bridges by determining (1) their free energy minimum, (2) their stiffness and (3) their contractile force.
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