Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Polymer adsorption at the ocular surface.

M A Lemp, E S Szymanski

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |February 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    A novel method quantifies polymer adsorption on the eye and rinsing resistance. Some artificial tear solutions mimic natural mucin, with two showing significant resistance to removal.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evaluation and differential diagnosis of keratoconjunctivitis sicca.

    The Journal of rheumatology. Supplement·2000
    Same author

    The 1998 Castroviejo Lecture. New strategies in the treatment of dry-eye states.

    Cornea·1999
    Same author

    Omafilcon A (Proclear) soft contact lenses in a dry eye population.

    The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc·1999
    Same author

    Epidemiology and classification of dry eye.

    Advances in experimental medicine and biology·1998
    Same author

    Sensitivity and specificity of a screening questionnaire for dry eye.

    Advances in experimental medicine and biology·1998
    Same author

    Meibomian gland dysfunction.

    Survey of ophthalmology·1996
    Same journal

    The economics of the initial preventive physical examination in medicare-reply.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    December 2011 archives web quiz winner.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    About this journal.

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    Same journal

    In memoriam: goodwin m. Breinin, MD (1918-2011).

    Archives of ophthalmology (Chicago, Ill. : 1960)·2013
    See all related articles

    Area of Science:

    • Ophthalmology
    • Materials Science
    • Biophysics

    Background:

    • Ocular surface hydration and lubrication depend on the tear film.
    • Polymers in artificial tears aim to improve lubrication and reduce dryness.
    • Understanding polymer adsorption and retention is crucial for effective artificial tear formulations.

    Purpose of the Study:

    • To develop and validate a new method for measuring polymer adsorption on ocular surfaces.
    • To assess the resistance of adsorbed polymers to removal by rinsing.
    • To characterize the adsorptive properties of artificial tear solutions and compare them to native mucin.

    Main Methods:

    • Development of a novel assay to quantify polymer adsorption in solution.
    • Measurement of polymer resistance to removal using a standardized rinsing protocol.

    Related Experiment Videos

  • Determination of adsorptive properties for various artificial tear formulations and purified mucin.

    • Main Results:

    • A new method for measuring ocular polymer adsorption and rinsing resistance was successfully developed.
    • The adsorptive properties of several artificial tear solutions were quantified.
    • Two tested solutions exhibited adsorptive properties comparable to mucin and demonstrated significant resistance to removal by rinsing.

    Conclusions:

    • The developed method provides a quantitative assessment of polymer-solution interaction with ocular surfaces.
    • Certain artificial tear formulations possess properties similar to natural mucin, suggesting potential for enhanced ocular surface protection.
    • The identification of rinsing-resistant polymers could inform the design of more durable and effective ocular surface treatments.