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Circadian regulation of the light input pathway in Neurospora crassa
M Merrow1, L Franchi, Z Dragovic
1Institute for Medical Psychology, University of Munich, D-80336 Munich, Germany.
Abstract:
FREQUENCY (FRQ) is a critical element of the circadian system of Neurospora. The white collar genes are important both for light reception and circadian function. We show that the responsiveness of the light input pathway is circadianly regulated. This circadian modulation extends to light-inducible components and functions that are not rhythmic themselves in constant conditions. FRQ interacts genetically and physically with WHITE COLLAR-1, and physically with WHITE COLLAR-2. These findings begin to address how components of the circadian system interact with basic cellular functions, in this case with sensory transduction.