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VISTA : visualizing global DNA sequence alignments of arbitrary length.

C Mayor1, M Brudno, J R Schwartz

  • 1National Energy Research Scientific Computing Center Genome Sciences Department, Berkeley, CA 94720, USA. vista@lbl.gov

Bioinformatics (Oxford, England)
|February 13, 2001
PubMed
Summary

VISTA is a web-based program for visualizing DNA sequence alignments. It offers clear output for identifying similarity and flexible configuration for various alignment lengths and resolutions.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • The VISTA server is accessible online.
  • Source code is available upon request.
  • Contact: vista@lbl.gov

Purpose of the Study:

  • To introduce VISTA, a novel program for visualizing DNA sequence alignments.
  • To highlight VISTA's capabilities in identifying sequence similarity.
  • To emphasize the program's accessibility and configurability for researchers.

Main Methods:

  • Development of a web-based visualization tool.
  • Implementation of configurable alignment viewing options.
  • Focus on clear and intuitive output generation.

Main Results:

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  • VISTA provides a clean output for easy identification of DNA sequence similarity.
  • The program is easily configurable for various alignment lengths and resolutions.
  • Web accessibility ensures broad researcher access.

Conclusions:

  • VISTA is a valuable tool for visualizing global DNA sequence alignments.
  • Its user-friendly interface and accessibility enhance its utility in genomic research.
  • The program facilitates the identification of sequence similarity across diverse alignment scales.