Related Experiment Video
Updated: Aug 12, 2026

Determining the Reactivity and Titre of Serum using a Haemagglutination Assay
Published on: January 29, 2010
An evaluation of serum thyroxine binding globulin as a routine test of thyroid function
Serum thyroxine binding globulin (TBG) values were correlated with other thyroid function test results and with the clinical condition in 680 patients. The estimation of serum TBG was helpful in the evaluation of thyroid status only in those patients who were either acutely ill, were taking the contraceptive pill, or were pregnant. Further, the derived index, thyroxine: TBG ratio, proved to be a better diagnostic index than the thyroxine:tri-iodothyronine uptake ratio and in many cases would have avoided the use of more expensive and time-consuming tests.
Serum thyroxine binding globulin (TBG) values were correlated with other thyroid function test results and with the clinical condition in 680 patients. The estimation of serum TBG was helpful in the evaluation of thyroid status only in those patients who were either acutely ill, were taking the contraceptive pill, or were pregnant. Further, the derived index, thyroxine: TBG ratio, proved to be a better diagnostic index than the thyroxine:tri-iodothyronine uptake ratio and in many cases would have avoided the use of more expensive and time-consuming tests.
Related Concept Videos
Serum Laboratory Studies, Stool Test, Breath Test
Drug Dosing in Renal Diseases: Measurement of Glomerular Filtration Rate
Serum Studies: Renal Function Tests
Graves Disease II: Pathophysiology

