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SPECT imaging of the dopamine transporter in juvenile-onset dystonia
J D O'Sullivan1, D C Costa, S Gacinovic
1Reta Lila Weston Institute of Neurological Studies, Royal Free and University College Medical School, University College London, UK.
Abstract:
Juvenile-onset dystonia that improves after levodopa may occur in both dopa-responsive dystonia (DRD) and juvenile parkinsonism (JP), clinically similar conditions with different prognoses and management goals. The authors show normal striatal uptake of the dopamine transporter ligand FP-CIT with SPECT in a clinically atypical case of DRD, in contrast to the reduced uptake observed in JP.
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