Hydrophobic Volume Effects in Albumin Solutions
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Updated: Oct 9, 2026

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
Published on: September 20, 2017
P. Schrade1, H. Klein, I. Egry
1Institut för Raumsimulation, DLR, Cologne, 51170, Germany
Abstract:
Density measurements of aqueous albumin solutions as a function of concentration and temperature are reported. The solvents were H(2)O, D(2)O, and a physiological H(2)O-based buffer. An anomaly of the density at very small concentrations of albumin in D(2)O was found. Furthermore, the partial specific volume of albumin is remarkably different in D(2)O and H(2)O. We attribute both effects to structural differences of the solvents. Copyright 2001 Academic Press.
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