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Microsphaeropsis olivacea keratitis and consecutive endophthalmitis.
C V Shah1, D B Jones, E R Holz
1Baylor College of Medicine, Cullen Eye Institute, Houston, Texas, USA.
American Journal of Ophthalmology
|February 13, 2001
Summary
A rare fungal infection, Microsphaeropsis olivacea, caused keratitis and endophthalmitis after eye injury. Prompt treatment with antifungals and corticosteroids led to resolution, though inflammation persisted.
Area of Science:
- Ophthalmology
- Medical Mycology
Background:
- Fungal keratitis and endophthalmitis are serious ocular infections.
- Microsphaeropsis olivacea is an uncommon cause of ocular infections.
Observation:
- A 51-year-old male presented with fungal keratitis and endophthalmitis following a penetrating eye injury.
- Aqueous humor cultures confirmed infection by M. olivacea.
Findings:
- Intraocular infection resolved rapidly with intraocular antifungal debridement, intravitreous amphotericin B, topical natamycin, and oral fluconazole.
- Persistent smoldering inflammation of the cornea and intraocular structures necessitated topical corticosteroid treatment.
Implications:
- Microsphaeropsis olivacea is a rare but significant ocular pathogen.
- Aggressive and prompt treatment is crucial for managing fungal keratitis and endophthalmitis, especially from unusual organisms.
- Early recognition of intraocular spread is vital for successful outcomes in fungal eye infections.