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A guide to 17beta-hydroxysteroid dehydrogenases
1GSF-National Research Center for Health and Environment, Institute for Experimental Genetics, Genome Analysis Center, Molecular Endocrinology and Proteomics Group, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Molecular and Cellular Endocrinology
|February 13, 2001
Abstract:
17beta-Hydroxysteroid dehydrogenases (17beta-HSD) are pivotal in controlling the biological potency of steroid hormones by catalyzing oxidation or reduction at position 17. Several 17beta-HSDs may as well metabolize further substrates including alcohols, bile acids, fatty acids and retinols. This review summarizes recent progress in the field of 17beta-HSD research provides an update of nomenclature.