Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lamellar body counts: a consensus on protocol.

M G Neerhof1, J C Dohnal, E R Ashwood

  • 1Department of Obstetrics and Gynecology, Northwestern University Medical School, Evanston Northwestern Healthcare, Evanston, Illinois, USA. m-neerhof@northwestern.edu

Obstetrics and Gynecology
|February 13, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Limits on WIMP Dark Matter with NaI(Tl) Crystals in Three Years of COSINE-100 Data.

Physical review letters·2025
Same author

Combined Annual Modulation Dark Matter Search with COSINE-100 and ANAIS-112.

Physical review letters·2025
Same author

Recent Developments in DFTB+, a Software Package for Efficient Atomistic Quantum Mechanical Simulations.

The journal of physical chemistry. A·2025
Same author

First Direct Search for Light Dark Matter Using the NEON Experiment at a Nuclear Reactor.

Physical review letters·2025
Same author

Search for Boosted Dark Matter in COSINE-100.

Physical review letters·2023
Same author

Erratum: "DFTB+, a software package for efficient approximate density functional theory based atomistic simulations" [J. Chem. Phys. 152, 124101 (2020)].

The Journal of chemical physics·2022
Same journal

The Political Determinants of Obstetric Prescribing.

Obstetrics and gynecology·2026
Same journal

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Adverse Maternal Pregnancy Outcomes: A Systematic Review and Meta-analysis.

Obstetrics and gynecology·2026
Same journal

Milestones in Motion: Vaginal Birth After Cesarean.

Obstetrics and gynecology·2026
Same journal

Ebola Virus in Pregnancy.

Obstetrics and gynecology·2026
Same journal

A Quality-Improvement Study Evaluating Three Postpartum Prophylactic Oxytocin Rates and Blood Loss After Vaginal Birth.

Obstetrics and gynecology·2026
Same journal

The Effects of Climate Change on Obstetric and Gynecologic Health.

Obstetrics and gynecology·2026
See all related articles

Lamellar body count, a rapid assay for fetal lung maturity, is standardized. Abandoning centrifugation and using specific counts for maturity (≥50,000/µL) or immaturity (≤15,000/µL) ensures accurate results.

Area of Science:

  • Neonatal Medicine
  • Clinical Chemistry
  • Pulmonary Medicine

Background:

  • Lamellar bodies are phospholipid packages storing pulmonary surfactant.
  • Lamellar body count (LBC) is a validated assay for fetal lung maturity.
  • Current LBC methods lack standardization, impacting result interpretation.

Framework:

  • Established a consensus for standardized lamellar body count methodology.
  • Involved institutions with prior LBC publication experience.
  • Focused on specimen preparation, particularly centrifugation.

Implementation:

  • Recommended abandoning centrifugation in specimen preparation.
  • Defined maturity threshold: 50,000 lamellar bodies/µL or greater.
  • Defined immaturity threshold: 15,000 lamellar bodies/µL or lower.

Related Experiment Videos

Implications:

  • Standardization ensures uniform and accurate LBC testing.
  • Reduces the risk of misinterpreting fetal lung maturity.
  • Facilitates wider adoption of LBC as a primary diagnostic assay.