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Updated: Oct 9, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Effect of low estrogen states in healthy women on dispersion of ventricular repolarization
1Tufts University School of Medicine-New England Medical Center, Boston, Massachusetts, USA. sabas@msx.upmc.edu
Abstract:
Our data show that although estrogen does not seem to affect the QT interval in healthy women, it significantly decreases the QT dispersion. This finding could provide an explanation to the gender differences in susceptibility to ventricular arrhythmias, besides the difference in the incidence of coronary artery disease.
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