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Updated: Aug 1, 2026

Identifying Protein-protein Interaction Sites Using Peptide Arrays
Published on: November 18, 2014
Applications of peptide arrays prepared by the SPOT-technology
U Reineke1, R Volkmer-Engert, J Schneider-Mergener
1Jerini AG, Rudower Chaussee 29, D-12489 Berlin, Germany. reineke@jerini.de
Abstract:
The growing range of applications for peptide arrays synthesized on coherent membranes by the SPOT-synthesis method proves they have emerged as a powerful proteomics technique to study molecular recognition events and identify biologically active peptides. Several developments, such as the introduction of novel polymeric surfaces, linkers, synthesis/cleavage strategies and detection methods, are facilitating an increasing spectrum of accessible compounds and applications in biological or pharmaceutical research.

