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Towards a truly integrative biology through the functional genomics of yeast
D Delneri1, F L Brancia, S G Oliver
1School of Biological Science, University of Manchester, 2.205 Stopford Building, Manchester Oxford Road, M13 9PT, UK. d.delneri@man.ac.uk
Current Opinion in Biotechnology
|February 13, 2001
Abstract:
A complete library of mutant Saccharomyces cerevisiae strains, each deleted for a single representative of yeast's 6000 protein-encoding genes, has been constructed. This represents a major biological resource for the study of eukaryotic functional genomics. However, yeast is also being used as a test-bed for the development of functional genomic technologies at all levels of analysis, including the transcriptome, proteome and metabolome.