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Mucor endophthalmitis.

A Bhansali1, A Sharma, A Kashyap

  • 1Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Acta Ophthalmologica Scandinavica
|February 13, 2001
PubMed
Summary

A rare case of type 2 diabetes presented with eyelid gangrene and endophthalmitis, indicating rhino-orbito-cerebral mucormycosis. Early recognition of this angio-invasive fungal infection is crucial for diabetic patients.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Endocrinology

Background:

  • Type 2 diabetes mellitus is a common metabolic disorder.
  • Rhino-orbito-cerebral mucormycosis (ROCM) is a rare, aggressive fungal infection.
  • ROCM often affects immunocompromised individuals, including diabetics.

Observation:

  • A patient with type 2 diabetes presented with sudden vision loss.
  • Clinical signs included eyelid gangrene and endophthalmitis.
  • Cranial CT revealed proptosis, ethmoid sinus mucosal thickening, and brain lesions.

Findings:

  • Vitreous humor analysis identified right-angle branched aseptate hyphae, characteristic of mucormycosis.
  • The findings confirmed ROCM as the cause of the presenting symptoms.

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  • The angio-invasive nature of the fungus was evident.

    • Implications:

    • This case highlights the importance of considering ROCM in diabetic patients with ophthalmic and neurological symptoms.
    • Prompt diagnosis and treatment of ROCM are critical to prevent severe morbidity and mortality.
    • Ophthalmologists and infectious disease specialists must be vigilant for this devastating fungal infection.