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Updated: Oct 9, 2026

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Published on: June 2, 2014
Migraine-associated vomiting and asystole in a child
J R Buchhalter1, G Berland, R Konkol
1Division of Pediatric Neurology, Oregon Health Sciences University, Portland, OR, USA.
Insights
Migraine can cause rare, life-threatening cardiac events in children. This case shows migraine-associated vomiting triggering cardiac asystole, successfully treated with a pacemaker.
Area of Science:
- Neurology
- Cardiology
- Pediatrics
Background:
- Autonomic nervous system dysfunction frequently accompanies migraine in pediatric and adult populations.
- While uncommon, significant cardiac rhythm disturbances can occur during migraine attacks, posing life-threatening risks.
Observation:
- A 3-year-old girl presented with migraine-associated vomiting.
- The vomiting episode precipitated a critical event of cardiac asystole.
Findings:
- The patient experienced cardiac asystole, a complete cessation of heartbeat, directly linked to migraine-induced vomiting.
- This life-threatening event was successfully managed and reversed through the implantation of a cardiac pacemaker.
Implications:
- This case highlights a rare but severe complication of migraine in a pediatric patient.
- It underscores the importance of considering cardiac events in children presenting with migraine and associated autonomic symptoms.
- Prompt recognition and intervention, such as pacemaker placement, can be life-saving in managing migraine-associated cardiac asystole.
Abstract:
A variety of symptoms that accompany migraine in the child and adult are mediated by the autonomic nervous system. Significant effects on cardiac rhythm are uncommon, but can be life threatening. We describe a 3-year-old girl in whom migraine-associated vomiting precipitated cardiac asystole which was effectively treated with a cardiac pacemaker.
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