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An infant with seizure-related bradycardia and asystole
P Venugopalan1, P M Nair, R L Koul
1Department of Child Health, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman. gopalax@omantel.net.omn
Insights
This case study highlights an infant with seizure-induced cardiac arrest (ictal bradycardia and asystole). Despite treatment, the infant died, emphasizing the critical need for recognizing and managing this rare event.
Area of Science:
- Pediatric Neurology
- Cardiology
- Epileptology
Background:
- Ictal bradycardia and asystole are rare but life-threatening autonomic disturbances during seizures.
- Prompt recognition and management are crucial for preventing sudden unexpected death in epilepsy (SUDEP).
Observation:
- A case of an infant girl experiencing ictal bradycardia and asystole during a seizure is presented.
- The infant received anti-epileptic therapy and a permanent cardiac pacemaker, yet succumbed during a seizure episode.
Findings:
- The study discusses the underlying mechanisms of ictal bradycardia and asystole.
- This event underscores the severity and potential lethality of seizure-related autonomic dysfunction.
Implications:
- Highlights the critical need for early recognition of ictal bradycardia and asystole in infants.
- Emphasizes the importance of integrated cardiac and neurological management for affected pediatric patients.
- Suggests that timely cardiac intervention and appropriate anticonvulsant therapy are essential for improving outcomes.
Abstract:
We describe an infant girl with ictal bradycardia and asystole who died during an episode of seizure, despite anti-epileptic therapy and permanent cardiac pacemaker implantation. The mechanism of ictal bradycardia and the need to recognize it are therefore discussed. Timely cardiac intervention and adequate anticonvulsant therapy are essential for successful management.