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Updated: Jul 17, 2026

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles
Published on: November 1, 2012
Does age play a role in mylohyoideus muscle function?
A Jégo1, P Chassagne, I Landrin-Dutot
1Service de Médecine Gériatrique and Digestive Tract Research Group, Hôpital Charles Nicolle, Rouen, France.
Age does not significantly impact mylohyoideus muscle asynchronisms during swallowing in healthy adults. Most asynchronisms are brief and occur frequently, with no linear relationship to aging.
Area of Science:
- Gerontology
- Physiology
- Neurology
Background:
- Swallowing disorders are common in the elderly population.
- The mylohyoideus muscle plays a crucial role in the initial phase of swallowing.
- Understanding age-related changes in muscle function is vital for geriatric health.
Purpose of the Study:
- To investigate the relationship between aging and mylohyoideus muscle contraction during swallowing.
- To determine if age affects the frequency and duration of mylohyoideus muscle asynchronisms.
Main Methods:
- A prospective study involving 120 healthy subjects across four age groups.
- Electromyographic (EMG) recording of mylohyoideus muscle activity during swallowing.
- Comparison of asynchronism frequency and duration among age cohorts.
Main Results:
- Mylohyoideus muscle asynchronisms were observed in 98% of subjects, predominantly short-lasting (<0.1s).
- No significant differences were found in the mean number, duration, or frequency of long-lasting asynchronisms across age groups.
- A linear relationship between asynchronism duration and aging was not identified in healthy elderly individuals.
Conclusions:
- Aging does not appear to linearly affect the duration or frequency of mylohyoideus muscle asynchronisms in healthy individuals.
- The presence of one or more long-lasting asynchronisms or at least six asynchronisms in 10 swallows may indicate an abnormality.
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