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Does local anesthesia at mid-trimester amniocentesis decrease pain experience? A randomized trial in 220 patients.

D Van Schoubroeck1, J Verhaeghe

  • 1Department of Obstetrics and Gynecology, Katholieke Universiteit Leuven, Belgium.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
|February 13, 2001
PubMed
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Mid-trimester amniocentesis is generally not painful. This study found that local anesthesia did not significantly alter patients' pain perception during the procedure.

Area of Science:

  • Obstetrics and Gynecology
  • Pain Management
  • Medical Procedures

Background:

  • Mid-trimester amniocentesis is a common prenatal diagnostic procedure.
  • Patient comfort and pain management are important considerations during invasive procedures.

Purpose of the Study:

  • To determine if local anesthesia reduces pain during mid-trimester amniocentesis.
  • To objectively assess the pain experience of patients undergoing this procedure.

Main Methods:

  • A randomized controlled trial was conducted.
  • Participants were allocated to receive either lignocaine 1% local anesthesia or no anesthesia prior to amniocentesis.
  • Pain was evaluated using five distinct scoring systems, including the Visual Analog Scale.

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Main Results:

  • The study included 220 women (114 received local anesthesia, 106 did not).
  • The mean Visual Analog Scale score was 1.4 (SD 1.5), with 97% reporting the procedure as not painful or bearable.
  • No statistically significant differences in pain experience were observed between the groups receiving local anesthesia and those who did not.

Conclusions:

  • Mid-trimester amniocentesis is typically a low-pain procedure.
  • The use of local anesthesia does not appear to significantly impact the pain experienced by patients during amniocentesis.