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Are Noonan syndrome and Noonan-like/multiple giant cell lesion syndrome distinct entities?
D R Bertola1, C A Kim, A C Pereira
1Clinical Genetics Unit, Department of Pediatrics, University of São Paulo, São Paulo, Brazil. drbertola@attglobal.net
American Journal of Medical Genetics
|February 13, 2001
Abstract:
We report on a family with typical clinical findings of Noonan syndrome associated with giant cell lesions in maxilla and mandible. We discuss the obvious clinical overlap between Noonan syndrome and Noonan-like/multiple giant cell lesion syndrome, and we give further clinical and molecular support that these two entities could be allelic conditions.
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