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Related Experiment Videos

Respiratory function in coffee workers.

E Zuskin, F Valić, Z Skurić

    British Journal of Industrial Medicine
    |May 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Coffee processing workers experience higher rates of respiratory symptoms and acute lung function decline, particularly affecting smaller airways. Pre-shift medication with disodium cromoglycate reduced these effects, suggesting dust exposure may cause lasting pulmonary damage.

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    Area of Science:

    • Occupational health
    • Environmental medicine
    • Pulmonary toxicology

    Background:

    • Workers in coffee processing facilities are exposed to airborne dust.
    • Previous studies suggest potential respiratory health risks associated with coffee dust exposure.

    Purpose of the Study:

    • To investigate the acute and potential chronic effects of coffee dust exposure on respiratory function in coffee processing workers.
    • To evaluate the efficacy of disodium cromoglycate in mitigating acute respiratory responses.

    Main Methods:

    • Cross-sectional study comparing respiratory symptoms and pulmonary function tests (maximum expiratory flow rate, FEV1.0) in three groups of coffee workers and a control group.
    • Measurements taken before and during work shifts, including Mondays and Thursdays.

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  • Intervention study involving administration of Intal (disodium cromoglycate) before work shifts.

    • Main Results:

    • Coffee workers exhibited a significantly higher prevalence of chronic respiratory symptoms compared to controls.
    • Acute, significant decreases in maximum expiratory flow rate at 50% and 25% vital capacity (VC) were observed during Monday work shifts (4.0-8.7% and 6.0-18.5%, respectively).
    • Acute reductions in FEV1.0 were less pronounced (1.3-2.8%). Disodium cromoglycate administration attenuated these acute reductions. Monday changes were more pronounced than Thursday changes, and acute decreases at low lung volumes suggest smaller airway involvement.

    Conclusions:

    • Occupational exposure to coffee dust is associated with increased chronic respiratory symptoms and acute, reversible declines in pulmonary function, primarily affecting smaller airways.
    • Disodium cromoglycate can reduce acute bronchoconstrictor effects, indicating an inflammatory or mediator-driven response.
    • Pre-shift pulmonary function values suggest that chronic exposure may lead to persistent loss of lung function in coffee processing workers.