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Immunogenicity of pneumococcal vaccine in heart transplant recipients
E A Blumberg1, S C Brozena, P Stutman
1Department of Medicine and MCP Hahnemann School of Medicine, Philadelphia, PA, USA. blumbere@mail.med.upenn.edu
Abstract:
To assess the immunogenicity of pneumococcal vaccine in recipients of heart transplants, we immunized 35 long-term transplantation survivors with pneumococcal vaccine and measured the pre- and postvaccination IgG antibody titers to 5 representative vaccine capsular polysaccharides. Responses of heart transplant recipients to pneumococcal vaccine antigens were generally suppressed.