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Updated: Aug 28, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Novel nonantibiotic therapies for pneumonia: cytokines and host defense
1Louisiana State University Health Sciences Center, Department of Medicine, 1901 Perdido St., New Orleans, LA 70112, USA. snelso1@lsuhsc.edu
Abstract:
Effective host defense against bacterial infection is dependent on the activation and recruitment of phagocytic cells. The initiation, maintenance, and resolution of this inflammatory response in the setting of bacterial pneumonia is dependent on the expression of cytokines. As the complexities of the host-pathogen interaction are further dissected and unraveled, immunologic manipulation of cytokine expression will likely become an important adjuvant therapy in the treatment of serious lung infections.
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