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Updated: Aug 19, 2026
11:27
Studying DNA Looping by Single-Molecule FRET
Published on: June 28, 2014
Rotor speed dependent sedimentation of circular and linear DNA
Biophysical Chemistry
|May 1, 1979
Abstract:
The sedimentation rate of large, linear DNA molecules has been shown to be rotor speed dependent (Rubenstein and Leighton, Biophys. Chem. 1 (1974)). In this communication we report the first studies designed to measure the rotor speed effect with a homogenous, linear viral DNA larger than bacteriophage T2 DNA. We also report the first studies using a homogenous, circular episomal DNA of known molecular weight. For this circular DNA a small rotor speed effect, previously unsuspected, was discovered.
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