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Updated: Sep 26, 2026

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
Published on: September 9, 2016
(-)-Argemonine hemihydrate
1Department of Inorganic Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic. man@chemi.muni.cz
Abstract:
(-)-Argemonine hemihydrate [systematic name: (6S,12S)-2,3,8,9-tetramethoxy-13-methyl-13-azadibenzo[b,f]bicyclo[3.3.1]nona-2,6-diene hemihydrate], C21H25NO4.0.5H2O, is a tertiary pavinane alkaloid. Both partially saturated nitrogen heterocycles adopt twisted half-chair conformations. The angle between the two aromatic rings is 86.90 (5) degrees.
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