Related Experiment Videos
Experimental Study on the Carcinogenicity of the Cytostatic Drug Ftorafur (Tegafur)
Laima Griciuté1, Vida Domkiené
1Lithuanian Oncological Center, Vilnius, Lithuania.
Pathology Oncology Research : POR
|January 1, 1996
Abstract:
Long-term carcinogenicity of Ftorafur (Tegafur) was studied in rodents. Rats and mice were treated for one year per os with 40 (mice) and 60 (rat) mg/kg Ftorafur twice a week and were followed for their entire life. Analysis of the data provide no evidence for the carcinogenicity of Ftorafur in rodents. These findings are similar to other antimetabolite studies and contrasts with the carcinogenic alkylating agents.