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Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations
J B Oldemeyer1, R J Lund, M Koch
1Department of Internal Medicine, Creighton University, Omaha, NE, USA.
Cardiology
|February 15, 2001
Abstract:
Statin-fibrate combinations are commonly used to treat hyperlipidemia. These drugs have been previously reported to cause rhabdomyolysis with acute renal failure. Whether different statin-fibrate combinations have different risks for rhabdomyolysis is not known. We report a patient who developed rhabdomyolysis with acute renal failure promptly after switching from the combination of pravastatin and fenofibrate to simvastatin and gemfibrozil.