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Late results of heart valve replacement with the Hancock II bioprosthesis

T E David1, J Ivanov, S Armstrong

  • 1Division of Cardiovascular Surgery of Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada. tirone.david@uhn.on.ca

The Journal of Thoracic and Cardiovascular Surgery
|February 15, 2001
PubMed

Insights

The Hancock II bioprosthesis shows good long-term durability and clinical outcomes in aortic and mitral valve replacement patients. This bioprosthetic valve is particularly effective in the aortic position for older individuals, offering functional improvement.

Area of Science:

  • Cardiovascular Surgery
  • Bioprosthetic Heart Valves
  • Clinical Outcomes Research

Background:

  • The Hancock II bioprosthesis is a commonly used option for aortic and mitral valve replacement.
  • Understanding the long-term performance and durability of bioprosthetic valves is crucial for patient management.

Purpose of the Study:

  • To evaluate the late clinical outcomes and durability of the Hancock II bioprosthesis in patients undergoing isolated aortic or mitral valve replacement.

Main Methods:

  • A prospective study of 670 patients with aortic valve replacement and 310 with mitral valve replacement using the Hancock II bioprosthesis.
  • Mean follow-up was over 80 months, with near-complete patient follow-up.

Main Results:

  • 15-year survival was 47% for aortic and 30% for mitral valve replacement.
  • Freedom from structural valve deterioration at 15 years was 81% (aortic) and 66% (mitral).
  • The majority of patients experienced functional improvement post-surgery.

Conclusions:

  • The Hancock II bioprosthesis demonstrates good clinical outcomes and durability, especially in the aortic position for older patients.
  • Factors like age, valve position, and ventricular function influence structural valve deterioration.
Abstract

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