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Heart failure and sleep-related breathing disorders
E Obenza Nishime1, L C Liu, T D Coulter
1Section of Heart Failure and Cardiac Transplantation Medicine, Department of Cardiology, Desk F25, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Heart failure (HF) is a serious condition. This review covers sleep-related breathing disorders in HF patients, including their features, causes, and new treatments.
Area of Science:
- Cardiology
- Sleep Medicine
- Pulmonology
Background:
- Heart failure (HF) persists as a significant clinical challenge despite medical and surgical advancements.
- The link between heart failure and sleep-related breathing disorders has been observed for over two centuries.
- Recent therapeutic developments now target sleep-related breathing disorders in HF patients.
Purpose of the Study:
- To provide a comprehensive overview of sleep-related breathing disorders in the context of heart failure.
- To discuss the clinical manifestations and underlying pathophysiology of these disorders.
- To review current and emerging treatment strategies for sleep-related breathing disorders in HF.
Main Methods:
- Literature review of clinical studies and observational data.
- Analysis of pathophysiological mechanisms linking HF and sleep-related breathing disorders.
- Synthesis of evidence on treatment efficacy and patient outcomes.
Main Results:
- Sleep-related breathing disorders are prevalent in HF patients.
- These disorders can exacerbate HF symptoms and negatively impact prognosis.
- Emerging treatments show promise in improving cardiovascular and respiratory parameters.
Conclusions:
- Sleep-related breathing disorders are integral to HF management.
- Targeting these disorders offers a valuable therapeutic avenue.
- Further research is needed to optimize treatment protocols and long-term outcomes.
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