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Related Experiment Videos

Comparison of Left Ventricular Ejection Fraction Calculation Methods.

Daniel J. Wilson1, Neshe North, Richard A. Wilson

  • 1Division of Cardiology, 885 Mission Street, Salem, OR 97302.

Echocardiography (Mount Kisco, N.Y.)
|February 15, 2001
PubMed
Summary
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The Teichholz method often overestimates left ventricular ejection fraction (LVEF) compared to other methods. The Quinones echocardiographic and 3-D nuclear methods provide similar LVEF measurements for assessing heart function.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Left ventricular ejection fraction (LVEF) is crucial for assessing systolic function.
  • Diverse imaging modalities are used for LVEF measurement, necessitating comparison.
  • Understanding inter-method variability is vital for clinical interpretation.

Purpose of the Study:

  • To compare LVEF measurements from Teichholz echocardiography, Quinones echocardiography, and 3-D gated thallium scintigraphy.
  • To determine the correlation and agreement between these LVEF assessment methods.

Main Methods:

  • Echocardiography (Teichholz and Quinones methods) and 3-D gated thallium scintigraphy were performed on 18 patients.
  • Imaging studies were completed within one hour of each other to minimize physiological changes.

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  • Statistical analysis included correlation coefficients (r) and standard error of the estimate (SEE).

    • Main Results:

    • The Teichholz method showed good correlation with the Quinones method (r=0.88) but consistently overestimated LVEF.
    • The Teichholz method demonstrated poor correlation with 3-D scintigraphy (r=0.7) and higher overestimation.
    • The Quinones method and 3-D scintigraphy correlated well (r=0.87) with similar LVEF estimates.

    Conclusions:

    • The Teichholz echocardiographic method tends to overestimate LVEF when compared to Quinones echocardiography and 3-D scintigraphy.
    • Quinones echocardiography and 3-D gated thallium scintigraphy yield comparable LVEF values.
    • Clinicians should be aware of potential overestimation by the Teichholz method in LVEF assessment.