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Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture

L E Young1, K Fernandes, T G McEvoy

  • 1Roslin Institute (Edinburgh), Roslin, Midlothian, Scotland, UK. Lorraine.Young@bbsrc.ac.uk

Nature Genetics
|February 15, 2001
PubMed

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
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