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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Percutaneous interventions on arterial conduits
M Zimarino1, A D Pichard, R De Caterina
1Department of Cardiology and Cardiac Surgery, University of Chieti, Italy. emosax@yahoo.com
Insights
Percutaneous interventions (PI) for arterial conduit dysfunction are increasingly explored. While challenging, PI can be safely performed on arterial grafts with careful planning and knowledge of graft pathophysiology.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Vascular Medicine
Background:
- Arterial conduits are extensively used in coronary surgery.
- Graft failure necessitates repeat surgeries, increasing patient risk.
- Percutaneous interventions (PI) are gaining interest for arterial conduit dysfunction.
Purpose of the Study:
- To evaluate the feasibility and safety of percutaneous interventions on arterial conduits.
- To review current evidence and challenges associated with PI in arterial grafts.
- To highlight the importance of planning and understanding graft pathophysiology for successful PI.
Main Methods:
- Review of existing single-center experiences and literature on PI of arterial conduits.
- Analysis of procedural challenges, including graft tortuosity, length, and spasm.
- Discussion of treatment strategies for ostial and anastomotic lesions, and management of steal phenomena.
Main Results:
- Few studies exist, mostly single-center, reporting short-term encouraging results.
- Restenosis rates are reported below 20% in available studies.
- Procedural failures are primarily linked to graft tortuosity, length, and spasm.
Conclusions:
- Percutaneous interventions can be safely performed on arterial grafts.
- Careful planning and understanding of conduit pathophysiology are crucial for success.
- Further large-scale studies are needed to confirm long-term efficacy and safety.
Abstract:
Because of the extensive use of arterial conduits for coronary surgery and the increased risk of repeat surgery in cases of graft failure, there is a growing interest in percutaneous interventions (PI) for patients with conduit dysfunction. PI on arterial conduits is a challenge for the interventional cardiologist, due to anatomic and functional characteristics of the graft. There are no large-scale multicenter or randomized studies focusing on PI of arterial conduits. Few single-center experiences are available, and all report short-term encouraging results and < 20% restenosis rates. Procedural failures are mainly due to graft tortuosity or length. Spasm is not rarely reported in muscular conduits. Stents are effective for the treatment of ostial disease and in bail-out cases, but should be cautiously used in anastomotic lesions. In patients with patent internal mammary artery, large pectoralis branches are sometimes considered responsible for steal phenomena, but flow diversion is usually trivial and embolization should be accomplished only after careful functional evaluations. PI can safely be performed on arterial grafts, with careful planning and knowledge of conduit pathophysiology.
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