Related Experiment Video
Updated: Jul 29, 2026

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
Published on: July 9, 2020
Intravascular flow prior to and following angioplasty in peripheral vessels (arteries)
1Institute of Diagnostic and Interventional Radiology, Clinic Nuremberg, Prof. E. Nathanstr. 1, Nuremberg, 90340, Germany.
Objectives:
The aim of this study was to assess mean values of velocities in peripheral arterial vessels prior to and following angioplasty in patients with peripheral arterial occlusive disease. Standard values are evaluated with the guidewire positioned proximal to the lesion, inside the lesion and distal to the lesion.
Methods:
Twenty-five measurements were taken prior to and following angioplasty in 22 patients with peripheral arterial occlusive disease. The Doppler guidewire was inserted over a 5 French sheath and a Cobra catheter. During measurements, the catheter was totally pulled back and the sheath was placed as proximal as possible.
Results:
Prior to angioplasty, the velocities in the arteries were 69 +/- 60 cm/second proximal to the lesion, 186 +/- 112 cm/second inside the stenoses and 47 +/- 36 cm/second distal to the lesion. The values increased to 97 +/- 105 cm/second, 89 +/- 89 cm/second and 83 +/- 72 cm/second, respectively. Proximal velocities were lower inside occlusions and increased more markedly compared to stenoses.
Conclusion:
The Doppler guidewire is a practical and valuable tool in assessing technical success after angioplasty of peripheral lesions. In successful angioplasties, no flow acceleration should be observed. Standard values were evaluated.
More Related Videos
07:25Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
13:48Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
Published on: April 21, 2023
Related Concept Videos
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Peripheral Artery Disease I: Introduction
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management